Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28438817 | 1.00 | MC4R (0.37) | MC4RKDM4ETDP1PAOXLMNA | |
| SCHEMBL18159311 | 0.84 | MC4R (0.30) | MC4R | |
| SCHEMBL31468630 | 0.77 | CSNK2A2 (0.35) | MC4RKDM4ETDP1PAOXLMNA | |
| SCHEMBL18958917 | 0.77 | LMNA (0.36) | LMNAHRH3 | |
| SCHEMBL28444430 | 0.74 | USP2 (0.44) | KDM4EALDH1A1HRH3ALOX15 | |
| SCHEMBL8952613 | 0.74 | HRH3 (0.39) | LMNAALDH1A1HRH4HRH3GAA | |
| SCHEMBL31468509 | 0.74 | KDM4E (0.33) | MC4RKDM4ETDP1CSNK2A2CSNK2B | |
| SCHEMBL3437040 | 0.72 | ALDH1A1 (0.58) | KDM4ELMNASIGMAR1ALDH1A1HRH3 | |
| SCHEMBL1229552 | 0.72 | CSNK2A2 (0.35) | MC4RKDM4EPAOXLMNACSNK2A2 | |
| SCHEMBL6143515 | 0.72 | PAOX (0.46) | MC4RPAOXLMNACSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325939-A2 | Process for preparing co-gels having polyazacycloalkane moieties and their use | L'Air Liquide S. A. à Directoire et Conseil de Surveillance pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) | 2003-07-09 | — | — | EP | claimed |