Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL597335 | 0.92 | MEN1 (0.31) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7081545 | 0.92 | CSNK2A2 (0.34) | KMT2AKDM4EALDH1A1LMNAHTT | |
| SCHEMBL3453582 | 0.91 | CDC7 (0.32) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL6160994 | 0.91 | KDM4E (0.32) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL6167207 | 0.90 | GPR142 (0.31) | KDM4EALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6973846 | 0.89 | — | — | |
| SCHEMBL6973278 | 0.89 | MEN1 (0.35) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL6957831 | 0.89 | GSK3B (0.30) | GSK3BCYP19A1 | |
| SCHEMBL6975056 | 0.87 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1CYP19A1 | |
| SCHEMBL6974565 | 0.86 | DHFR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0786455-B1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO (JP) | 2003-12-03 | — | — | EP | disclosed |
| US-6147097-A | METHOD FOR TREATING AIDS | SHIONOGI & CO., LTD. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5910506-A | IMIDAZOLE DERIVATIVES, E.G.5-(3,5-DICHLOROPHENYLTHIO)-1,2-DIMETHYL-4-ISOPROPYL-1H-IMIDAZOLE; VIRICIDES; AIDS; NONTOXIC | SHIONOGI & CO., LTD. (JP) | 1999-06-08 | — | — | US | disclosed |
| EP-0786455-A1 | IMIDAZOLE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 1997-07-30 | — | — | EP | disclosed |