Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4557719 | 0.79 | CYP2C19 (0.43) | DUTCYP2C19ACLYTSHRLMNA | |
| SCHEMBL4224462 | 0.79 | CYP2C19 (0.55) | DUTCYP2C19ACLYTSHRMTOR | |
| SCHEMBL21596172 | 0.74 | IDO1 (0.53) | CYP2C19TSHRLMNAALDH1A1HPGD | |
| SCHEMBL6264569 | 0.73 | CA12 (0.49) | DUTCYP2C19TSHRALDH1A1KMT2A | |
| SCHEMBL6639307 | 0.73 | LMNA (0.42) | CYP2C19ACLYTSHRLMNASRC | |
| SCHEMBL12696974 | 0.72 | DUT (0.52) | DUTACLYTSHRLMNAMTOR | |
| SCHEMBL4910864 | 0.70 | KMT2A (0.47) | DUTTSHRKMT2ACA12CA2 | |
| SCHEMBL4046527 | 0.70 | CYP2C19 (0.45) | CYP2C19TSHRLMNAALDH1A1HPGD | |
| SCHEMBL4910866 | 0.70 | KMT2A (0.47) | DUTTSHRKMT2ACA12CA2 | |
| SCHEMBL6265169 | 0.69 | SLC6A9 (0.44) | ACLYALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |