Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 3/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 7/20 | 0.37 |
| ▸ | CFTR | P13569 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082580 | 0.91 | REN (0.44) | RENSSTR5CFTR | |
| SCHEMBL7078288 | 0.89 | REN (0.43) | RENSSTR5CFTR | |
| SCHEMBL7079907 | 0.87 | REN (0.43) | RENSSTR5CFTR | |
| SCHEMBL7077413 | 0.86 | REN (0.43) | RENSSTR5 | |
| SCHEMBL6042477 | 0.85 | REN (0.47) | RENSSTR5CFTRALDH1A1HTT | |
| SCHEMBL7076766 | 0.84 | REN (0.54) | RENSSTR5 | |
| SCHEMBL7079908 | 0.84 | REN (0.52) | RENSSTR5 | |
| SCHEMBL7082883 | 0.83 | REN (0.46) | RENSSTR5ALDH1A1 | |
| SCHEMBL7084760 | 0.83 | REN (0.54) | RENSSTR5ALDH1A1 | |
| SCHEMBL7079331 | 0.83 | REN (0.46) | RENSSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0783496-B9 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0783496-B1 | THIAZOLIDINEDIONE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-26 | — | — | EP | disclosed |
| US-5965589-A | AN ACTIVE MATERIAL HAVING HYPOGLYCEMIC ACTIVITY AND BLOOD LIPID LOWERING ACTIVITY, FOR USE AS AN ANTIDIABETIC AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-12 | — | — | US | disclosed |