SCHEMBL3576571

SCHEMBL3576571

COC(=O)c1cccc(-c2cccc(C(=O)OC)c2C(=O)OC)c1C(=O)OC

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
CA9 Q16790 2/20 0.59
CA12 O43570 1/20 0.59
CA7 P43166 1/20 0.59
CA14 Q9ULX7 1/20 0.59
TSHR P16473 2/20 0.55
LMNA P02545 1/20 0.55
PTPRC P08575 1/20 0.54
ALDH1A1 P00352 1/20 0.53
CFTR P13569 1/20 0.53
HSD17B10 Q99714 1/20 0.53
SLC6A3 Q01959 5/20 0.53
SLC6A4 P31645 3/20 0.53
MAPT P10636 3/20 0.53
KMT2A Q03164 2/20 0.53
MEN1 O00255 1/20 0.53
HTT P42858 1/20 0.53
MAPK10 P53779 1/20 0.53
PTK2B Q14289 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1666445 0.91 CA1 (0.64) CA1CA2CA9CA12CA7
SCHEMBL69682 0.89 SLC6A3 (0.57) CA1CA2CA9CA12CA7
SCHEMBL10425360 0.88 CA12 (0.55) CA1CA2CA9CA12CA7
SCHEMBL9815483 0.85 CA1 (0.57) CA1CA2CA9CA12CA7
SCHEMBL4856223 0.85 SLC6A3 (0.54) CA1CA2CA9CA12CA7
SCHEMBL773429 0.83 CA1 (0.55) CA1CA2CA9CA12CA7
SCHEMBL29453452 0.83 CA1 (0.80) CA1CA2CA9CA12CA7
SCHEMBL6598415 0.83 CA1 (0.55) CA1CA2CA9CA12CA7
SCHEMBL8669428 0.83 CA1 (0.55) CA1CA2CA9CA12CA7
SCHEMBL157121 0.83 CA1 (0.80) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61249977-A None JP disclosed
JP-60089444-A None JP disclosed
WO-2023157770-A1 COMPOUND PRODUCTION METHOD 株式会社カネカ 2023-08-24 WO disclosed
US-9469621-B2 Method for producing multisubstituted biphenyl compound and solid catalyst to be used therein KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-10-18 US disclosed
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN UBE CORPORATION (JP) 2015-10-01 US disclosed
EP-2738009-A1 COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING ORIGINAL PLATE FOR LASER ENGRAVING AND PRODUCTION METHOD THEREFOR, PRODUCTION METHOD FOR RELIEF PRINTING PLATE, AND RELIEF PRINTING PLATE FUJIFILM Corporation (JP) 2014-06-04 EP disclosed
US-20140130692-A1 COMPOSITION FOR LASER ENGRAVING, RELIEF PRINTING PLATE PRECURSOR FOR LASER ENGRAVING AND PROCESS FOR PRODUCING SAME, PROCESS FOR MAKING RELIEF PRINTING PLATE, AND RELIEF PRINTING PLATE FUJIFILM CORPORATION (JP) 2014-05-15 US disclosed
US-8492565-B2 Biphenyltetracarboxylic acid dianhydride and process for producing the same, and polyimide formed from the same and process for producing the same MITSUBISHI CHEMICAL CORPORATION (JP) 2013-07-23 US disclosed
US-20130178597-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND MATERIALS TO BE USED IN PRODUCING SAME UBE INDUSTRIES, LTD. (JP) 2013-07-11 US disclosed
EP-2597111-A1 POLYIMIDE PRECURSOR, POLYIMIDE, AND MATERIALS TO BE USED IN PRODUCING SAME Ube Industries, Ltd. (JP) 2013-05-29 EP disclosed
US-20040039222-A1 Process for production of biphenyltetracarboxylic acid tetraesters UBE INDUSTRIES, LTD. (JP) 2004-02-26 US disclosed
EP-0556806-B1 Process for producing biphenyltetracarboxylic dianhydride MITSUBISHI CHEM CORP (JP) 1996-05-29 EP disclosed
EP-0421046-B1 Process for producing highly pure 3,3',4,4' - biphenyltetra- carboxylic acid or dianhydride thereof HITACHI LTD (JP) 1995-06-14 EP disclosed
US-5258530-A Process for producing biphenyltetracarboxylic dianhydride MITSUBISHI KASEI CORPORATION (JP) 1993-11-02 US disclosed
EP-0556806-A1 Process for producing biphenyltetracarboxylic dianhydride Mitsubishi Chemical Corporation (JP) 1993-08-25 EP disclosed
US-4895596-A Method of recovering palladium catalyst UBE INDUSTRIES, LTD. (JP) 1990-01-23 US disclosed
JP-S61249977-A PRODUCTION OF BIPHENYLTETRACARBOXYLIC ACID DIANHYDRIDE OF HIGH PURITY MITSUBISHI CHEM IND LTD 1986-11-07 JP disclosed
WO-1986001200-A1 PROCESS FOR PREPARAING TETRAMETHYL BIPHENYLTETRACARBOXYLATE MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1986-02-27 WO disclosed
JP-S6089444-A PRODUCTION OF BIPHENYLTETRACARBOXYLIC ACID MITSUBISHI CHEM IND LTD 1985-05-20 JP disclosed
US-3940426-A CRYSTALLIZATION OF ISOMERS UBE INDUSTRIES, LTD. (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040039222-A1 Process for production of biphenyltetracarboxylic acid tetraesters PCCA, DDT, DECR2 CA1 241/4885CA2 340/4885CA9 414/4885
US-20150274689-A1 METHOD FOR PRODUCING MULTISUBSTITUTED BIPHENYL COMPOUND AND SOLID CATALYST TO BE USED THEREIN DDT, CYP1A1, CYP1B1 CA1 3481/4885CA2 4534/4885CA9 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.