Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7905929 | 1.00 | NR3C1 (0.77) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL8197072 | 0.91 | NR3C1 (0.75) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL8068364 | 0.87 | NR3C1 (1.00) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL7899988 | 0.87 | NR3C1 (0.69) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL7081817 | 0.86 | NR3C1 (0.70) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL8674574 | 0.86 | NR3C1 (0.70) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL7894330 | 0.86 | NR3C1 (0.62) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL7903153 | 0.86 | NR3C1 (0.65) | NR3C1CYP3A4PGRARLMNA | |
| SCHEMBL8138913 | 0.85 | NR3C1 (0.66) | NR3C1CYP3A4PGRARUSP2 | |
| SCHEMBL7894324 | 0.85 | NR3C1 (0.68) | NR3C1CYP3A4PGRARUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173430-B1 | ENANTIOMERS OF MERCAPTO LACTONES AND PROCESSES FOR THEIR SYNTHESIS | GLAXO GROUP LTD (GB) | 2003-07-09 | — | — | EP | disclosed |
| EP-1173430-A1 | ENANTIOMERS OF MERCAPTO LACTONES AND PROCESSES FOR THEIR SYNTHESIS | GLAXO GROUP LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064882-A2 | ENANTIOMERS OF MERCAPTO LACTONES AND PROCESSES FOR THEIR SYNTHESIS | GLAXO GROUP LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |