Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.50 |
| ▸ | CTSL | P07711 | 12/20 | 0.45 |
| ▸ | CTSB | P07858 | 7/20 | 0.45 |
| ▸ | CTSK | P43235 | 7/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.39 |
| ▸ | CTRL | P40313 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971609 | 0.90 | CTSS (0.52) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6109161 | 0.89 | CTSS (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7083037 | 0.88 | CTSL (0.43) | CTSSCTSLCTSBCTSKPSMB8 | |
| SCHEMBL6964964 | 0.85 | CTSS (0.53) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6957068 | 0.84 | CTSS (0.52) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6969684 | 0.84 | CTSS (0.54) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6964214 | 0.82 | CTSS (0.68) | CTSSCTSLCTSB | |
| SCHEMBL5357617 | 0.80 | CTSS (0.48) | CTSSCTSLCTSBCTSKOPRL1 | |
| SCHEMBL6966523 | 0.80 | CTSS (0.51) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7085808 | 0.79 | CTSL (0.56) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |