Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.52 |
| ▸ | CTSL | P07711 | 10/20 | 0.47 |
| ▸ | CTSK | P43235 | 7/20 | 0.47 |
| ▸ | CTSB | P07858 | 7/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081891 | 0.90 | CTSS (0.50) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6106584 | 0.89 | CTSS (0.57) | CTSSCTSLCTSKCTSBTACR2 | |
| SCHEMBL6961882 | 0.87 | CTSL (0.44) | CTSSCTSLCTSKCTSBTACR2 | |
| SCHEMBL6964964 | 0.87 | CTSS (0.53) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6957068 | 0.86 | CTSS (0.52) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6969684 | 0.86 | CTSS (0.54) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6964214 | 0.84 | CTSS (0.68) | CTSSCTSLCTSB | |
| SCHEMBL6966523 | 0.82 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL6973986 | 0.81 | CTSS (0.63) | CTSSCTSLCTSB | |
| SCHEMBL6964222 | 0.80 | CTSS (0.67) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-B1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMA (US) | 2003-07-02 | — | — | EP | claimed |