Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.51 |
| ▸ | CTSL | P07711 | 10/20 | 0.50 |
| ▸ | CTSS | P25774 | 5/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14299552 | 0.86 | CTSK (0.46) | CTSKCTSLCTSSIDO1TDO2 | |
| SCHEMBL19933193 | 0.79 | CTRB1 (0.62) | CTSKCTSLCTSSATMCTRB1 | |
| SCHEMBL19569920 | 0.78 | POLB (0.61) | CTSKCTSLCTSSATMCTRB1 | |
| SCHEMBL27351869 | 0.77 | SYK (0.63) | CTSKCTSLCTSSATMCTRB1 | |
| SCHEMBL22144261 | 0.77 | CTSK (0.66) | CTSKCTSLCTSSCTRB1CTSB | |
| SCHEMBL6827337 | 0.77 | CTSK (0.56) | CTSKCTSLCTSSATMCTRB1 | |
| SCHEMBL329038 | 0.77 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL265783 | 0.77 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL20381057 | 0.77 | CTSK (0.66) | CTSKCTSLCTSSCTRB1CTSB | |
| SCHEMBL265461 | 0.77 | CTSK (0.66) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184388-B1 | SULPHOSTIN ANALOGUES AND PROCESSES FOR THE PREPARATION OF SULPHOSTIN AND ANALOGUES THEREOF | ZAIDAN HOJIN BISEIBUTSU (JP) | 2003-07-30 | — | — | EP | disclosed |
| US-6579989-B1 | Dipeptidylpeptidase IV inhibitors; hormone and immune modu-laters; anti-HIV and antiallergenic agents | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1184388-A1 | SULPHOSTIN ANALOGUES AND PROCESSES FOR THE PREPARATION OF SULPHOSTIN AND ANALOGUES THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 2002-03-06 | — | — | EP | disclosed |