SCHEMBL265783

SCHEMBL265783

CCC[C@@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTSK P43235 6/20 0.66
SIRT2 Q8IXJ6 1/20 0.61
SIRT1 Q96EB6 1/20 0.61
CTSL P07711 5/20 0.60
CTSS P25774 5/20 0.60
CTSB P07858 3/20 0.55
MME P08473 1/20 0.54
ECE1 P42892 1/20 0.54
ALDH1A1 P00352 1/20 0.54
ALOX15 P16050 1/20 0.54
PPARG P37231 1/20 0.54
PPARA Q07869 1/20 0.54
TACR1 P25103 2/20 0.53
KYNU Q16719 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329038 1.00 CTSK (0.66) CTSKSIRT2SIRT1CTSLCTSS
SCHEMBL265461 1.00 CTSK (0.66) CTSKSIRT2SIRT1CTSLCTSS
SCHEMBL11332452 0.92 CTSL (0.72) CTSKSIRT2SIRT1CTSLCTSS
SCHEMBL150166 0.92 CTSL (0.72) CTSKSIRT2SIRT1CTSLCTSS
SCHEMBL4126228 0.92 CTSL (0.72) CTSKSIRT2SIRT1CTSLCTSS
SCHEMBL20381057 0.91 CTSK (0.66) CTSKSIRT2SIRT1CTSLCTSS
SCHEMBL22144261 0.91 CTSK (0.66) CTSKSIRT2SIRT1CTSLCTSS
SCHEMBL17279329 0.90 SIRT2 (0.74) SIRT2SIRT1CTSLCTSSMME
SCHEMBL11308449 0.90 SIRT2 (0.74) SIRT2SIRT1CTSLCTSSMME
Hydrochloric Acid SCHEMBL4438043 0.90 CTSL (0.70) CTSKSIRT2SIRT1CTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 US disclosed
CN-110869375-B 2-oxo-1-imidazolidinylimidazothiadiazole derivatives UCB生物制药有限责任公司 2022-08-30 CN disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 WO disclosed
US-11155564-B2 2-oxo-1-imidazolidinyl imidazothiadiazole derivatives UCB Biopharma SRL 2021-10-26 US disclosed
EP-3652182-B1 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES UCB Biopharma SRL (BE) 2021-09-08 EP disclosed
EP-3652182-A1 2-OXO-1-IMIDAZOLIDINYL IMIDAZOTHIADIAZOLE DERIVATIVES UCB Biopharma SRL (BE) 2020-05-20 EP disclosed
US-20030139377-A1 Fab I inhibitors SMITHKLINE BEECHAM CORPORATION 2003-07-24 US disclosed
US-6503903-B1 Administering 3-oxo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine-7-carboxamide derivative SMITHKLINE BEECHAM CORPORATION 2003-01-07 US disclosed
EP-1171428-A1 FAB I INHIBITORS SmithKline Beecham Corporation (US) 2002-01-16 EP disclosed
WO-2000063187-A1 FAB I INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2000-10-26 WO disclosed
US-4894464-A ARTIFICIAL SWEETENERS PFIZER INC. (US) 1990-01-16 US disclosed
US-4855454-A CHEMICAL INTERMEDIATES; SWEETENERS PFIZER INC. (US) 1989-08-08 US disclosed
US-4804782-A ARTIFICIAL SWEETENER PFIZER, INC. (US) 1989-02-14 US disclosed
EP-0034876-B1 BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF PFIZER INC. (US) 1984-08-29 EP disclosed
US-4411925-A STABLE SWEETENERS PFIZER INC. (US) 1983-10-25 US disclosed
EP-0034876-A2 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1981-09-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139377-A1 Fab I inhibitors SERPINB1, TFPI, TFPI2 CTSK 169/4885SIRT2 2148/4885SIRT1 2179/4885
US-11155564-B2 2-oxo-1-imidazolidinyl imidazothiadiazole derivatives CYP3A4, CYP3A43, CYP3A7 CTSK 859/4885SIRT2 764/4885SIRT1 1235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.