SCHEMBL7082484

SCHEMBL7082484

O=C(O)CCCOc1ccc(C(O)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
ALDH1A1 P00352 2/20 0.49
RAB9A P51151 1/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
FFAR4 Q5NUL3 4/20 0.48
FFAR1 O14842 3/20 0.48
CYP2C9 P11712 1/20 0.48
SCN5A Q14524 1/20 0.48
USP2 O75604 1/20 0.47
PPARA Q07869 3/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 1/20 0.45
CNR1 P21554 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.44
ALPL P05186 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120716 0.89 KMT2A (0.58) HPGDKMT2AMEN1ALDH1A1RAB9A
SCHEMBL7086688 0.88 PPARA (0.56) KMT2AMEN1ALDH1A1HTTFFAR4
SCHEMBL3190012 0.86 PTGDR2 (0.50) HPGDKMT2AMEN1ALDH1A1RAB9A
SCHEMBL6438739 0.85 PDE4B (0.53) HPGDALDH1A1FFAR4FFAR1PPARA
SCHEMBL13940016 0.85 L3MBTL1 (0.66) HPGDKMT2AMEN1ALDH1A1HTT
SCHEMBL6439692 0.85 PDE4B (0.53) HPGDALDH1A1FFAR4FFAR1PPARA
SCHEMBL28536384 0.84 PPARA (0.63) HPGDKMT2AMEN1ALDH1A1RAB9A
Formic Acid SCHEMBL3827570 0.83 PPARA (0.53) HPGDKMT2AMEN1ALDH1A1RAB9A
SCHEMBL8921579 0.82 PPARA (0.61) HPGDKMT2AMEN1ALDH1A1RAB9A
SCHEMBL8922627 0.82 PPARA (0.61) HPGDKMT2AMEN1ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003068806-A1 SOLID PHASE PEPTIDE SYNTHESIS ON SILICA JOHNSON MATTHEY PLC (GB) 2003-08-21 WO claimed
WO-2003068806-A1 SOLID PHASE PEPTIDE SYNTHESIS ON SILICA JOHNSON MATTHEY PLC (GB) 2003-08-21 WO disclosed