Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 13/20 | 0.47 |
| ▸ | THRB | P10828 | 13/20 | 0.47 |
| ▸ | RHEB | Q15382 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082561 | 0.93 | THRA (0.52) | THRATHRBRHEB | |
| SCHEMBL1642681 | 0.93 | THRA (0.52) | THRATHRBRHEB | |
| SCHEMBL7082555 | 0.89 | THRA (0.54) | THRATHRB | |
| SCHEMBL6268671 | 0.87 | THRA (0.50) | THRATHRB | |
| SCHEMBL6273680 | 0.83 | THRB (0.51) | THRATHRB | |
| SCHEMBL1642280 | 0.78 | THRA (0.49) | THRATHRBRHEB | |
| SCHEMBL1641910 | 0.77 | THRB (0.54) | THRATHRB | |
| SCHEMBL1640505 | 0.75 | THRB (0.47) | THRATHRBRHEB | |
| SCHEMBL1643112 | 0.75 | THRA (0.56) | THRATHRBRHEB | |
| SCHEMBL6270950 | 0.74 | ALDH1A1 (0.44) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030078289-A1 | Indole carboxylic acids as thyroid receptor ligands | ASPNES GARY E (US) | 2003-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078289-A1 | Indole carboxylic acids as thyroid receptor ligands | THRA, MC1R, THRB | THRA 1/4885THRB 3/4885RHEB 1413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.