Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081866 | 0.88 | GAA (0.42) | CA12CA1CA2CA9TRPA1 | |
| SCHEMBL7081915 | 0.83 | HSD17B2 (0.41) | CA1CA2TRPA1PTGS1CACNA1C | |
| SCHEMBL7077940 | 0.83 | GAA (0.45) | CA1CA2LMNATSHRHTT | |
| SCHEMBL7080898 | 0.82 | HSD17B2 (0.43) | CA12CA1CA2CA9TRPA1 | |
| SCHEMBL7077790 | 0.79 | BRD4 (0.40) | CA12CA9PTGS1MAPTALDH1A1 | |
| SCHEMBL7080937 | 0.78 | TP53 (0.39) | LMNATSHRCASP1HTTPOLB | |
| SCHEMBL4830292 | 0.77 | NPY2R (0.49) | CA12CA1CA2CA9LMNA | |
| SCHEMBL7637220 | 0.74 | GBA1 (0.47) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6669968 | 0.73 | CA2 (0.55) | CA12CA1CA2CA9CA14 | |
| SCHEMBL212443 | 0.72 | KMT2A (0.46) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068204-A1 | SYNTHESIS OF SUBSTITUTED SULFONYL AMINES | Grünenthal GmbH (DE) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068204-A1 | SYNTHESIS OF SUBSTITUTED SULFONYL AMINES | Grünenthal GmbH (DE) | 2003-08-21 | — | — | WO | disclosed |