Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082810 | 0.78 | CA12 (0.39) | LMNAALDH1A1TSHRCASP1HTT | |
| SCHEMBL7081866 | 0.75 | GAA (0.42) | LMNAALDH1A1TSHRCASP1HTT | |
| SCHEMBL7077790 | 0.73 | BRD4 (0.40) | ALDH1A1KDM4EMAPTNPSR1 | |
| SCHEMBL7081915 | 0.71 | HSD17B2 (0.41) | ALDH1A1MEN1KMT2ANPSR1HSD17B2 | |
| SCHEMBL7077940 | 0.71 | GAA (0.45) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL7080898 | 0.70 | HSD17B2 (0.43) | MAPTHSD17B2GAA | |
| SCHEMBL6669968 | 0.69 | CA2 (0.55) | LMNAMEN1KMT2ATSHRCASP1 | |
| SCHEMBL13204260 | 0.68 | GAA (0.53) | LMNAALDH1A1TSHRCASP1KDM4E | |
| SCHEMBL563388 | 0.68 | ALDH1A1 (0.55) | LMNAALDH1A1TSHRCASP1KDM4E | |
| Water SCHEMBL2538022 | 0.66 | ALDH1A1 (0.53) | LMNAALDH1A1TSHRCASP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068204-A1 | SYNTHESIS OF SUBSTITUTED SULFONYL AMINES | Grünenthal GmbH (DE) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068204-A1 | SYNTHESIS OF SUBSTITUTED SULFONYL AMINES | Grünenthal GmbH (DE) | 2003-08-21 | — | — | WO | disclosed |