Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7082944 | 1.00 | HSD11B1 (0.51) | HSD11B1MEN1KMT2AFBP1 | |
| SCHEMBL7080287 | 0.86 | HSD11B1 (0.52) | HSD11B1MEN1KMT2AFBP1 | |
| SCHEMBL7079599 | 0.86 | HSD11B1 (0.52) | HSD11B1MEN1KMT2AFBP1 | |
| SCHEMBL7079650 | 0.85 | FBP1 (0.41) | HSD11B1MEN1KMT2AFBP1 | |
| SCHEMBL7082452 | 0.84 | HSD11B1 (0.39) | HSD11B1MEN1KMT2A | |
| SCHEMBL7079469 | 0.82 | FBP1 (0.44) | HSD11B1FBP1 | |
| SCHEMBL7083810 | 0.79 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL7079477 | 0.74 | HSD11B1 (0.57) | HSD11B1MEN1KMT2A | |
| SCHEMBL6897711 | 0.69 | HSD11B1 (0.62) | HSD11B1MEN1KMT2A | |
| SCHEMBL7813280 | 0.68 | HSD11B1 (1.00) | HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003064372-A1 | 2-ADAMANTYLALKYLAMINES AND THEIR USE IN THE TREATMENT OF CONDITIONS GENERALLY ASSOCIATED WITH ABNORMALITIES IN GLUTAMATERGIC TRANSMISSION | VERNALIS RESEARCH LIMITED (GB) | 2003-08-07 | — | — | WO | disclosed |