Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1970488 | 0.87 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL291947 | 0.84 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL291949 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL291948 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL4067427 | 0.83 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL4303842 | 0.82 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL16310441 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2CYP1A2TSHRGAA | |
| SCHEMBL1970486 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL299909 | 0.79 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 | |
| SCHEMBL3327050 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2CYP1A2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325016-A2 | NUCLEOSIDE DERIVATIVES AND A METHOD FOR PRODUCING THE SAME | Epigenomics AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| WO-2001012642-A2 | NUCLEOSIDE DERIVATIVES AND A METHOD FOR PRODUCING SAME | EPIGENOMICS AG (DE) | 2001-02-22 | — | — | WO | disclosed |