Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291947 | 0.88 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL7083080 | 0.87 | ALDH1A1 (0.50) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL4067427 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL291948 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL291949 | 0.87 | ALDH1A1 (0.56) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL1970486 | 0.86 | ALDH1A1 (0.49) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL4303842 | 0.86 | ALDH1A1 (0.62) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL16310441 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL7644179 | 0.84 | ALDH1A1 (0.52) | ALDH1A1CYP1A2TSHRSMN1; SMN2POLB | |
| SCHEMBL2949624 | 0.83 | MEN1 (0.42) | ALDH1A1CYP1A2TSHRHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110724733-B | Sequencing chip for high-resolution space transcriptome | 东南大学 | 2022-11-11 | — | — | CN | claimed |
| US-20210380629-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTOACTIVATED AGENTS | VIBRANT HOLDINGS, LLC | 2021-12-09 | — | — | US | claimed |
| EP-3790985-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTACTIVATED AGENTS | Vibrant Holdings, LLC (US) | 2021-03-17 | — | — | EP | claimed |
| WO-2019217704-A9 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTACTIVATED AGENTS | VIBRANT HOLDINGS, LLC (US) | 2020-12-10 | — | — | WO | claimed |
| CN-110724733-A | Sequencing chip for high-resolution space transcriptome | 东南大学 | 2020-01-24 | — | — | CN | claimed |
| WO-2019217704-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTACTIVATED AGENTS | VIBRANT HOLDINGS, LLC (US) | 2019-11-14 | — | — | WO | claimed |
| US-20070060744-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. (US) | 2007-03-15 | — | — | US | claimed |
| US-20060014943-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. (US) | 2006-01-19 | — | — | US | claimed |
| US-6962991-B2 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. (US) | 2005-11-08 | — | — | US | claimed |
| US-20050101763-A1 | Synthesis of photolabile 2-(2-nitrophenyl)propyloxycarbonyl protected amino acids | TRUSTEES OF BOSTON UNIVERSITY (US) | 2005-05-12 | — | — | US | claimed |
| US-20040191824-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. | 2004-09-30 | — | — | US | claimed |
| US-20030078413-A1 | Process for the synthesis of pyrazolopyrimidines | EPOCH BIOSCIENCES, INC. | 2003-04-24 | — | — | US | claimed |
| EP-3504251-B1 | NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME | UNIV COLORADO REGENTS (US) | 2026-03-25 | — | — | EP | disclosed |
| US-12187851-B2 | Network polymers and methods of making and using same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2025-01-07 | — | — | US | disclosed |
| US-20230119934-A1 | NETWORK POLYMERS AND METHODS OF MAKING AND USING SAME | UNIV COLORADO REGENTS (US) | 2023-04-20 | — | — | US | disclosed |
| US-11535713-B2 | Network polymers and methods of making and using same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2022-12-27 | — | — | US | disclosed |
| WO-2000061594-A2 | NUCLEOSIDE DERIVATIVES WITH PHOTO-UNSTABLE PROTECTIVE GROUPS | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2000-10-19 | — | — | WO | disclosed |
| US-5763599-A | FOR LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON DNA CHIP | Pfleiderer, Wolfgang (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0797580-A2 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | Pfleiderer, Wolfgang (DE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018634-A2 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 1996-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078413-A1 | Process for the synthesis of pyrazolopyrimidines | DPYD, PNP, UMPS | ALDH1A1 1288/4885CYP1A2 1248/4885TSHR 2182/4885 |
| US-20060014943-A1 | Process for the synthesis of pyrazolopyrimidines | DPYD, PNP, UMPS | ALDH1A1 1288/4885CYP1A2 1248/4885TSHR 2182/4885 |
| US-20210380629-A1 | METHODS OF SYNTHESIZING A POLYNUCLEOTIDE ARRAY USING PHOTOACTIVATED AGENTS | POLN, PCNA, POLM | ALDH1A1 2604/4885CYP1A2 4153/4885TSHR 3755/4885 |
| US-20070060744-A1 | Process for the synthesis of pyrazolopyrimidines | DPYD, PNP, UMPS | ALDH1A1 1288/4885CYP1A2 1248/4885TSHR 2182/4885 |
| US-20050101763-A1 | Synthesis of photolabile 2-(2-nitrophenyl)propyloxycarbonyl protected amino acids | NPPA, DNPEP, NPEPPS | ALDH1A1 4813/4885CYP1A2 4303/4885TSHR 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.