SCHEMBL7083160

SCHEMBL7083160

CC(=O)OC(C)C(=O)N=C(N)N

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
TBXA2R P21731 1/20 0.33
GALR3 O60755 1/20 0.32
MAPT P10636 1/20 0.32
BLM P54132 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083154 0.75 TSHR (0.39) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL351872 0.74
SCHEMBL16382192 0.74 MMP1 (0.35) TSHRSMN1; SMN2
SCHEMBL17236094 0.74
SCHEMBL27478846 0.72 TSHR (0.41) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL5696108 0.71
SCHEMBL11612645 0.70 TSHR (0.42) TSHRCHRM2CHRM4CHRM1TBXA2R
Hydrochloric Acid SCHEMBL27585259 0.68 TSHR (0.46) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL16316794 0.68
SCHEMBL359717 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003068807-A2 ECHINOCANDIN CYCLIC PEPTIDE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-08-21 WO disclosed