⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319249 | 0.76 | — | — | |
| SCHEMBL11385340 | 0.74 | — | — | |
| SCHEMBL7083188 | 0.70 | — | — | |
| SCHEMBL9392012 | 0.67 | — | — | |
| SCHEMBL7564006 | 0.67 | — | — | |
| SCHEMBL6431331 | 0.65 | MEN1 (0.33) | — | |
| SCHEMBL17961910 | 0.65 | — | — | |
| SCHEMBL7601080 | 0.64 | KDM4E (0.32) | — | |
| SCHEMBL2359993 | 0.63 | NPSR1 (0.35) | — | |
| SCHEMBL3856071 | 0.61 | NPSR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0768879-B1 | THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS | BASF AG (DE) | 2003-03-19 | — | — | EP | disclosed |
| US-5958923-A | TREATMENT OF NERVOUS SYSTEM DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| EP-0592453-B1 | AMINOALKYL-SUBSTITUTED 2-AMINO-1,3,4-THIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 1998-12-16 | — | — | EP | disclosed |
| EP-0768879-A1 | USE OF THIAZOLE AND THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-23 | — | — | EP | disclosed |
| WO-1996002249-A1 | USE OF THIAZOLE AND THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS | BASF AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |
| US-5424312-A | Treating central nervous system disorders, high blood pressure | BASF AKTIENGESELLSCHAFT (DE) | 1995-06-13 | — | — | US | disclosed |
| EP-0592453-A1 | AMINOALKYL-SUBSTITUTED 2-AMINO-1,3,4-THIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1994-04-20 | — | — | EP | disclosed |
| WO-1992022541-A1 | AMINOALKYL-SUBSTITUTED 2-AMINO-1,3,4-THIADIAZOLES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | WO | disclosed |