SCHEMBL6431331

SCHEMBL6431331

C=CCSc1nnsc1N

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 2/20 0.33
HSD17B10 Q99714 2/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7581317 0.78 SMN1; SMN2 (0.34) MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL8536797 0.77 ALDH1A1 (0.36) MEN1KMT2ASMN1; SMN2ALDH1A1ALOX15
SCHEMBL7081943 0.73 LMNA (0.36) MEN1KMT2AALDH1A1ALOX15MAPK1
SCHEMBL7594898 0.68 ALDH1A1 (0.36) ALDH1A1ALOX15
SCHEMBL29082169 0.67 ALDH1A1 (0.34) ALDH1A1ALOX15MAPK1HSD17B10LMNA
SCHEMBL11666474 0.67 MEN1 (0.38) MEN1KMT2ASMN1; SMN2ALDH1A1ALOX15
SCHEMBL3763261 0.67 ALDH1A1 (0.34) ALDH1A1ALOX15
SCHEMBL7083190 0.65
SCHEMBL8536794 0.65 ALDH1A1 (0.33) MEN1KMT2ASMN1; SMN2ALDH1A1ALOX15
SCHEMBL7790910 0.65 ALDH1A1 (0.36) MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5200102-A Oil additive which is a reaction product of a polymer containing ethylene, an alpha-monoolefin and an olefinic carboxylic acid acylating agent and an amino alkylthio thiadiazole TEXACO INC. (US) 1993-04-06 US claimed
US-6916767-B2 Antioxidant amines based on n-(4aniliophenyl) amides antioxidant amines based on n-(4-anilinophenyl) amides UNIROYAL CHEMICAL COMPANY, INC. (US) 2005-07-12 US disclosed
EP-1252209-B1 COMPOSITIONS COMPRISING ANTIOXIDANT AMINES BASED ON N-(4-ANILINOPHENYL) AMIDES UNIROYAL CHEM CO INC (US) 2004-11-03 EP disclosed
EP-0961789-B1 LUBRICANTS CONTAINING ASHLESS ANTIWEAR-DISPERSANT ADDITIVE HAVING VISCOSITY INDEX IMPROVER CREDIT UNIROYAL CHEM CO INC (US) 2003-07-09 EP disclosed
EP-0768879-B1 THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS BASF AG (DE) 2003-03-19 EP disclosed
US-20030030033-A1 Antioxidant amines based on n-(4aniliophenyl) amides Antioxidant amines based on n-(4-anilinophenyl) Amides LANXESS SOLUTIONS US INC. 2003-02-13 US disclosed
EP-1252209-A1 COMPOSITIONS COMPRISING ANTIOXIDANT AMINES BASED ON N-(4-ANILINOPHENYL) AMIDES Uniroyal Chemical Company, Inc. (US) 2002-10-30 EP disclosed
CN-1070486-C Fluorothiadiazolyloxyacetamide BAYER AG (DE) 2001-09-05 CN disclosed
WO-2001049761-A1 COMPOSITIONS COMPRISING ANTIOXIDANT AMINES BASED ON N-(4-ANILINOPHENYL)AMIDES UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-07-12 WO disclosed
CN-1288888-A Intermediates for the preparation of fluorothiadiazolyloxyacetamides BAYER AG (DE) 2001-03-28 CN disclosed
EP-0815093-A1 HERBICIDE FLUOROTHIADIAZOLYL OXYACETAMIDES BAYER AG (DE) 1998-01-07 EP disclosed
US-5698500-A POLYMER CONTAINING ETHYLENE, AN ALPHA MONOOLEFIN AND A POLYENE WITH A 2-MERCAPTO-1,3,4-THIADIAZOLE MOIETY GRAFTED THEREON UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-12-16 US disclosed
EP-0768879-A1 USE OF THIAZOLE AND THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS BASF AKTIENGESELLSCHAFT (DE) 1997-04-23 EP disclosed
WO-1996028434-A1 HERBICIDE FLUOROTHIADIAZOLYL OXYACETAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1996-09-19 WO disclosed
WO-1996002249-A1 USE OF THIAZOLE AND THIADIAZOLE COMPOUNDS AS D3 DOPAMINE RECEPTOR LIGANDS BASF AKTIENGESELLSCHAFT (DE) 1996-02-01 WO disclosed
US-5401743-A Treatment of high blood pressure, Parkinson*s disease, schizophrenia, dopamine receptors BASF AKTIENGESELLSCHAFT (DE) 1995-03-28 US disclosed
EP-0596891-A1 AMINOALKYL-SUBSTITUTED 2-AMINO-5-MERCAPTOTHIADIAZOLES, THEIR PREPARATION AND THEIR USE BASF Aktiengesellschaft (DE) 1994-05-18 EP disclosed
US-5200102-A Oil additive which is a reaction product of a polymer containing ethylene, an alpha-monoolefin and an olefinic carboxylic acid acylating agent and an amino alkylthio thiadiazole TEXACO INC. (US) 1993-04-06 US disclosed
US-5200102-A Oil additive which is a reaction product of a polymer containing ethylene, an alpha-monoolefin and an olefinic carboxylic acid acylating agent and an amino alkylthio thiadiazole TEXACO INC. (US) 1993-04-06 US disclosed
WO-1992022542-A1 AMINOALKYL-SUBSTITUTED 2-AMINO-5-MERCAPTOTHIADIAZOLES, THEIR PREPARATION AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 1992-12-23 WO disclosed