Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.42 |
| ▸ | MTTP | P55157 | 4/20 | 0.41 |
| ▸ | APOB | P04114 | 2/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792205 | 0.91 | MTTP (0.47) | RXFP1HDAC1HDAC6MTTPAPOB | |
| SCHEMBL27583427 | 0.90 | PDE2A (0.46) | PDE2ASORT1MTTPAPOBTACR1 | |
| SCHEMBL28752149 | 0.83 | PDE2A (0.48) | RXFP1PDE2ASORT1MTTPAPOB | |
| SCHEMBL6800458 | 0.80 | MTTP (0.49) | MTTPAPOBPPARA | |
| SCHEMBL6795009 | 0.76 | MTTP (0.55) | RXFP1HDAC1MTTPAPOB | |
| SCHEMBL7613184 | 0.76 | MTTP (0.52) | RXFP1HDAC1HDAC6MTTPAPOB | |
| SCHEMBL7134000 | 0.76 | ITGB1 (0.49) | RXFP1MTTPAPOBPTPRBPPARA | |
| SCHEMBL7084265 | 0.75 | KMT2A (0.59) | RXFP1SORT1 | |
| SCHEMBL6800762 | 0.74 | EPHX2 (0.45) | HDAC1HDAC6CA1CA2HPGD | |
| SCHEMBL7086952 | 0.74 | PLG (0.53) | RXFP1MTTPAPOBCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |