Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.43 |
| ▸ | MTTP | P55157 | 3/20 | 0.43 |
| ▸ | APOB | P04114 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799904 | 0.89 | MTTP (0.50) | PDE2AAURKAAURKBMTTPAPOB | |
| SCHEMBL27583427 | 0.87 | PDE2A (0.46) | PDE2ACA12CA1CA2CA9 | |
| SCHEMBL7083522 | 0.83 | RXFP1 (0.45) | PDE2ACA12CA1CA2CA9 | |
| SCHEMBL7084075 | 0.82 | CA12 (0.43) | CA12CA1CA2CA9MTTP | |
| SCHEMBL7086952 | 0.81 | PLG (0.53) | CA12CA1CA2CA9MTTP | |
| SCHEMBL7083682 | 0.81 | CA12 (0.45) | CA12CA1CA2CA9APOB | |
| SCHEMBL7079790 | 0.80 | S1PR1 (0.51) | MTTPAPOBITGB1ITGA4RXFP1 | |
| SCHEMBL28752147 | 0.79 | PDE2A (0.45) | PDE2ACA1CA2CNR2TACR1 | |
| SCHEMBL7081600 | 0.78 | SORT1 (0.53) | PDE2AMTTPAPOBRXFP1SORT1 | |
| SCHEMBL6792746 | 0.78 | PTGS1 (0.57) | CA12CA1CA2CA9MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1478077-A | Benzamide compounds as APO B secretion inhibitors | ����ҩƷ��ҵ��ʽ���� | 2004-02-25 | — | — | CN | disclosed |