SCHEMBL6792205

SCHEMBL6792205

CC(C)(C)OC(=O)Nc1cccc(C(=O)NCc2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)n1

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MTTP P55157 13/20 0.47
APOB P04114 5/20 0.47
HDAC1 Q13547 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
RXFP1 Q9HBX9 1/20 0.44
UGCG Q16739 2/20 0.44
GAA P10253 1/20 0.42
SMO Q99835 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083522 0.91 RXFP1 (0.45) MTTPAPOBHDAC1HDAC6RXFP1
SCHEMBL6800458 0.89 MTTP (0.49) MTTPAPOBGAASMO
SCHEMBL6795009 0.86 MTTP (0.55) MTTPAPOBHDAC1RXFP1GAA
SCHEMBL7613184 0.84 MTTP (0.52) MTTPAPOBHDAC1HDAC6RXFP1
SCHEMBL6799904 0.83 MTTP (0.50) MTTPAPOBGAASMO
SCHEMBL6789351 0.83 MTTP (0.49) MTTPAPOBRXFP1UGCGGAA
SCHEMBL6787835 0.82 MTTP (0.47) MTTPAPOBRXFP1UGCGSMO
SCHEMBL7085681 0.81 MTTP (0.47) MTTPAPOBRXFP1UGCGGAA
SCHEMBL7610927 0.80 MTTP (0.51) MTTPAPOBHDAC1RXFP1
SCHEMBL6796384 0.80 SMO (0.55) MTTPAPOBGAASMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MTTP 363/4885APOB 1/4885HDAC1 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.