Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.32 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083615 | 1.00 | POLB (0.37) | POLBKLK7KLK5SCN9AEPHX2 | |
| SCHEMBL7688087 | 0.91 | POLB (0.39) | POLBKLK7KLK5SCN9AEPHX2 | |
| SCHEMBL7688088 | 0.91 | POLB (0.39) | POLBKLK7KLK5SCN9AEPHX2 | |
| SCHEMBL6961824 | 0.81 | PABPC1 (0.42) | SCN9APABPC1KMT2AKDM4EMAPT | |
| SCHEMBL6961818 | 0.81 | PABPC1 (0.42) | SCN9APABPC1KMT2AKDM4EMAPT | |
| SCHEMBL6955844 | 0.81 | SCN9A (0.35) | SCN9APABPC1 | |
| SCHEMBL6968925 | 0.80 | SCN9A (0.34) | KLK7KLK5SCN9APABPC1 | |
| SCHEMBL6955835 | 0.80 | KLK7 (0.41) | KLK7KLK5SCN9ATLR2TLR1 | |
| SCHEMBL6955840 | 0.80 | KLK7 (0.41) | KLK7KLK5SCN9ATLR2TLR1 | |
| SCHEMBL6968920 | 0.79 | KLK7 (0.42) | KLK7KLK5SCN9APABPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015444-B1 | PYRIMIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP LTD (KR) | 2003-05-28 | — | — | EP | disclosed |