Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PTGFR | P43088 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6490478 | 0.90 | TRPV1 (0.51) | ALDH1A1SMO | |
| SCHEMBL7080544 | 0.89 | MAPT (0.47) | RAB9ANPC1TAS1R3TAS1R1CNR1 | |
| SCHEMBL6681168 | 0.89 | RAB9A (0.46) | RAB9ANPC1TAS1R3TAS1R1CNR1 | |
| SCHEMBL6498735 | 0.85 | RAB9A (0.46) | RAB9ANPC1TAS1R3TAS1R1CNR1 | |
| SCHEMBL6681166 | 0.84 | RAB9A (0.43) | RAB9ANPC1TAS1R3TAS1R1CNR1 | |
| SCHEMBL6796673 | 0.84 | HTT (0.59) | RAB9ANPC1CNR1MAPTHTT | |
| SCHEMBL6492508 | 0.82 | SMN1; SMN2 (0.52) | RAB9ANPC1TAS1R3TAS1R1CNR1 | |
| SCHEMBL6791511 | 0.82 | HTT (0.57) | RAB9ANPC1CNR1MAPTHTT | |
| Hydrochloric Acid SCHEMBL7079728 | 0.82 | SMN1; SMN2 (0.51) | RAB9ANPC1TAS1R3TAS1R1MAPT | |
| SCHEMBL6683560 | 0.82 | CTNNB1 (0.46) | RAB9ANPC1TAS1R3TAS1R1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |