Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083706 | 0.89 | RAB9A (0.46) | MAPTSMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL6796673 | 0.87 | HTT (0.59) | MAPTHTTLMNARAB9ANPC1 | |
| SCHEMBL6791511 | 0.85 | HTT (0.57) | MAPTHTTLMNARAB9ANPC1 | |
| SCHEMBL7086601 | 0.84 | SMN1; SMN2 (0.53) | MAPTSMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL6795959 | 0.84 | MAPT (0.58) | MAPTSMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL6681168 | 0.84 | RAB9A (0.46) | MAPTSMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL6793890 | 0.83 | RAB9A (0.54) | MAPTSMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL7080737 | 0.83 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL6498735 | 0.82 | RAB9A (0.46) | MAPTSMN1; SMN2HTTLMNARAB9A | |
| SCHEMBL6492508 | 0.82 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2HTTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |