Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 2/20 | 0.46 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498735 | 0.84 | RAB9A (0.46) | CTNNB1TCF7L2IRAK4RAB9ANPC1 | |
| SCHEMBL6681168 | 0.83 | RAB9A (0.46) | CTNNB1TCF7L2IRAK4RAB9ANPC1 | |
| SCHEMBL6682890 | 0.82 | SYK (0.46) | RAB9ANPC1SMN1; SMN2SMOSYK | |
| SCHEMBL7083706 | 0.82 | RAB9A (0.46) | CTNNB1TCF7L2IRAK4RAB9ANPC1 | |
| SCHEMBL6498069 | 0.81 | HDAC7 (0.49) | CTNNB1TCF7L2RAB9ANPC1MAPT | |
| SCHEMBL6492508 | 0.81 | SMN1; SMN2 (0.52) | CTNNB1TCF7L2RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL7079728 | 0.80 | SMN1; SMN2 (0.51) | CTNNB1TCF7L2RAB9ANPC1MAPT | |
| SCHEMBL6796673 | 0.80 | HTT (0.59) | RAB9ANPC1MAPTCNR1SMO | |
| SCHEMBL7080851 | 0.80 | SMO (0.49) | RAB9ANPC1MAPTSMN1; SMN2TAS1R3 | |
| SCHEMBL7086601 | 0.79 | SMN1; SMN2 (0.53) | CTNNB1TCF7L2IRAK4RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | claimed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | claimed |