Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 4/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6800933 | 0.87 | SIRT1 (0.44) | MAPK14DDR2MAPK13MAPK12DDR1 | |
| SCHEMBL6794653 | 0.77 | PSMD10 (0.35) | MAPK14ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL6800670 | 0.75 | KMT2A (0.56) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL7366081 | 0.72 | STAT3 (0.42) | ALDH1A1LMNAKMT2AMEN1PSMD10 | |
| SCHEMBL2656976 | 0.71 | SIRT1 (0.44) | ALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL3868295 | 0.71 | CA12 (0.41) | ALDH1A1KMT2AMEN1PSMD10 | |
| SCHEMBL6489184 | 0.71 | KDM4E (0.40) | ALDH1A1PSMD10NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3483301 | 0.70 | PSMD10 (0.41) | ALDH1A1MAPTPOLBKMT2AMEN1 | |
| SCHEMBL60443 | 0.69 | STAT3 (0.50) | ALDH1A1LMNAKMT2AMEN1PKM | |
| SCHEMBL15456206 | 0.69 | LMNA (0.41) | ALDH1A1MAPTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |