Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070535 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL7089130 | 0.80 | SLC40A1 (0.57) | MEN1KMT2ASLC40A1TDP1 | |
| SCHEMBL6456741 | 0.80 | KDM4E (0.63) | ALDH1A1GAAMEN1KMT2ALMNA | |
| SCHEMBL30925424 | 0.73 | SLC40A1 (0.74) | ALDH1A1HTTMEN1KMT2ASLC40A1 | |
| SCHEMBL27214265 | 0.73 | SLC40A1 (0.74) | ALDH1A1HTTMEN1KMT2ASLC40A1 | |
| SCHEMBL2568163 | 0.68 | GAA (0.64) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL1030675 | 0.68 | BACE1 (0.64) | ALDH1A1HTTMEN1KMT2ASLC40A1 | |
| SCHEMBL30471546 | 0.68 | SLC40A1 (0.53) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL22765014 | 0.68 | SLC40A1 (0.53) | ALDH1A1HTTGAAMEN1KMT2A | |
| SCHEMBL13485913 | 0.67 | PTGES2 (0.45) | ALDH1A1HTTMEN1KMT2ASLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144507-A1 | Sulfonamide-containing heterocyclic compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144507-A1 | Sulfonamide-containing heterocyclic compounds | SLC5A2, SLC5A1, CBR3 | ALDH1A1 1018/4885HTT 2163/4885GAA 2149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.