Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 9/20 | 0.57 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CKS1B | P61024 | 3/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3071874 | 0.81 | SLC40A1 (0.47) | SLC40A1GLO1KMT2ACA2SMN1; SMN2 | |
| SCHEMBL7083753 | 0.80 | ALDH1A1 (0.48) | SLC40A1KMT2ATDP1MEN1 | |
| SCHEMBL3072255 | 0.79 | SLC40A1 (0.59) | SLC40A1GLO1KMT2ACA2SMN1; SMN2 | |
| SCHEMBL18423255 | 0.76 | KMT2A (0.60) | SLC40A1GLO1KMT2ACA2SMN1; SMN2 | |
| SCHEMBL15228476 | 0.74 | PIM1 (0.48) | KMT2ASMN1; SMN2TDP1MEN1 | |
| SCHEMBL30925462 | 0.73 | SLC40A1 (1.00) | SLC40A1GLO1KMT2ATDP1MEN1 | |
| SCHEMBL11973652 | 0.73 | SLC40A1 (1.00) | SLC40A1GLO1KMT2ATDP1MEN1 | |
| SCHEMBL1702487 | 0.71 | KMT2A (0.47) | SLC40A1KMT2ASMN1; SMN2TDP1MEN1 | |
| SCHEMBL27680502 | 0.71 | POLB (0.46) | SLC40A1GLO1KMT2AKEAP1NFE2L2 | |
| SCHEMBL6811801 | 0.70 | SLC40A1 (0.56) | SLC40A1GLO1KMT2ACA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144507-A1 | Sulfonamide-containing heterocyclic compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2003-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144507-A1 | Sulfonamide-containing heterocyclic compounds | SLC5A2, SLC5A1, CBR3 | SLC40A1 2821/4885GLO1 652/4885KMT2A 1187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.