Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.48 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | APOB | P04114 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079806 | 0.88 | NPC1 (0.49) | RXFP1TMPRSS4NPC1RAB9APTGS1 | |
| SCHEMBL6793819 | 0.86 | RXFP1 (0.55) | RXFP1MLYCDNPC1RAB9APTGS1 | |
| SCHEMBL7086631 | 0.85 | NPC1 (0.54) | RXFP1TMPRSS4NPC1RAB9APTGS1 | |
| SCHEMBL7133291 | 0.84 | NPC1 (0.56) | NPC1RAB9APTGS1SMN1; SMN2CHRNB2 | |
| SCHEMBL6792746 | 0.84 | PTGS1 (0.57) | TMPRSS4NPC1RAB9APTGS1SMN1; SMN2 | |
| SCHEMBL7087379 | 0.82 | RXFP1 (0.57) | RXFP1NPC1RAB9APTGS1SMN1; SMN2 | |
| SCHEMBL7086952 | 0.81 | PLG (0.53) | RXFP1NPC1RAB9APTGS1SMN1; SMN2 | |
| SCHEMBL7079790 | 0.81 | S1PR1 (0.51) | RXFP1NPC1RAB9APTGS1SMN1; SMN2 | |
| SCHEMBL16088831 | 0.81 | CHRNB2 (0.71) | TMPRSS4CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7079526 | 0.80 | MCHR1 (0.48) | NPC1RAB9APTGS1SMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |