Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.67 |
| ▸ | PPARG | P37231 | 16/20 | 0.67 |
| ▸ | PPARD | Q03181 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855260 | 0.81 | PPARA (0.74) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL27508133 | 0.81 | PPARA (0.64) | PPARAPPARGPPARD | |
| SCHEMBL5855953 | 0.81 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5857062 | 0.81 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5858178 | 0.81 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL5382866 | 0.80 | PPARG (0.58) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL5857599 | 0.79 | PPARG (0.62) | PPARAPPARGPPARDKDM4EHRH3 | |
| SCHEMBL5855374 | 0.78 | PPARG (0.82) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL5856037 | 0.78 | PPARG (0.82) | PPARAPPARGPPARDKDM4E | |
| SCHEMBL5857695 | 0.78 | PPARG (0.82) | PPARAPPARGPPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030166697-A1 | Heterocyclic compounds | NIPPON SHINYAKU CO., LTD. (JP) | 2003-09-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030166697-A1 | Heterocyclic compounds | LIPE, GPR119, LIPC | PPARA 660/4885PPARG 701/4885PPARD 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.