Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 7/20 | 0.68 |
| ▸ | HSD17B2 | P37059 | 7/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 3/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.52 |
| ▸ | BCR | P11274 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675046 | 0.88 | HSD17B1 (0.63) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| SCHEMBL31574448 | 0.88 | HSD17B1 (0.63) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| SCHEMBL29696046 | 0.88 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| SCHEMBL29429121 | 0.88 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| SCHEMBL26979937 | 0.88 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| SCHEMBL272034 | 0.88 | HSD17B1 (0.68) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| SCHEMBL20056522 | 0.86 | HSD17B1 (0.63) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| Hydrogen Sulfide SCHEMBL6269773 | 0.85 | HSD17B1 (0.65) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| Hydrogen Sulfide SCHEMBL22042810 | 0.85 | HSD17B1 (0.65) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 | |
| SCHEMBL3811825 | 0.85 | HSD17B1 (0.72) | HSD17B1HSD17B2ESR2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030139479-A1 | Non-halogenated biphenyl triol compounds, antimicrobial compositions containing the same, and methods of using the same | WARNER-LAMBERT COMPANY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139479-A1 | Non-halogenated biphenyl triol compounds, antimicrobial compositions containing the same, and methods of using the same | AS3MT, PTPN1, NONO | HSD17B1 1934/4885HSD17B2 2032/4885ESR2 1268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.