Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 4/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | APOB | P04114 | 2/20 | 0.41 |
| ▸ | MTTP | P55157 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079735 | 0.90 | SORT1 (0.42) | SORT1APOBMTTPCA12CA1 | |
| SCHEMBL6792150 | 0.90 | MTTP (0.49) | NR3C1APOBMTTP | |
| SCHEMBL7134201 | 0.80 | LRRK2 (0.51) | SORT1 | |
| SCHEMBL6792606 | 0.80 | MTTP (0.49) | APOBMTTP | |
| SCHEMBL6679626 | 0.79 | SORT1 (0.40) | SORT1ITGB1ITGA4 | |
| SCHEMBL7084265 | 0.78 | KMT2A (0.59) | SORT1 | |
| SCHEMBL6492676 | 0.77 | MTTP (0.41) | SORT1APOBMTTPGCGR | |
| SCHEMBL7083682 | 0.77 | CA12 (0.45) | APOBCA12CA1CA2CA9 | |
| SCHEMBL7133280 | 0.76 | SORT1 (0.43) | SORT1APOBMTTPCA12CA1 | |
| SCHEMBL6792560 | 0.76 | SMO (0.57) | NR3C1APOBMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |