Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.44 |
| ▸ | SRPK3 | Q9UPE1 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PTAFR | P25105 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792412 | 0.90 | ADRB3 (0.54) | ADRB1ADRB3LMNAMAPTXBP1 | |
| SCHEMBL7084233 | 0.80 | SORT1 (0.45) | SORT1 | |
| SCHEMBL7079735 | 0.79 | SORT1 (0.42) | MAPTSORT1KMT2A | |
| SCHEMBL7079790 | 0.76 | S1PR1 (0.51) | LMNASMN1; SMN2HIF1AEPAS1 | |
| SCHEMBL6800223 | 0.75 | ADRB1 (0.53) | LRRK2ADRB1ADRB3LMNAMAPT | |
| SCHEMBL6798640 | 0.75 | HIF1A (0.53) | LRRK2ADRB1ADRB3LMNAMAPT | |
| SCHEMBL6793989 | 0.75 | TRPV1 (0.48) | SMN1; SMN2SORT1 | |
| SCHEMBL7086952 | 0.74 | PLG (0.53) | LRRK2LMNASMN1; SMN2 | |
| SCHEMBL7086631 | 0.74 | NPC1 (0.54) | LMNASMN1; SMN2 | |
| SCHEMBL6666916 | 0.73 | CYP11B1 (0.55) | LRRK2SORT1CYP11B1CYP11B2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |