SCHEMBL7084337

SCHEMBL7084337

Cc1nc(-c2cccc(CCCCN(C(=O)O)c3ccc(Br)cc3)c2)no1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.44
L3MBTL1 Q9Y468 3/20 0.43
DAO P14920 1/20 0.40
SPHK2 Q9NRA0 5/20 0.38
SPHK1 Q9NYA1 5/20 0.38
MET P08581 1/20 0.38
RAB9A P51151 3/20 0.38
TSHR P16473 2/20 0.38
NPC1 O15118 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7075442 0.77 TSHR (0.45) FFAR4L3MBTL1DAORAB9ATSHR
SCHEMBL7084329 0.76 L3MBTL1 (0.43) FFAR4L3MBTL1DAOMETRAB9A
SCHEMBL7097280 0.76 MAPT (0.45) FFAR4L3MBTL1DAORAB9ANPC1
SCHEMBL7072311 0.75 L3MBTL1 (0.43) L3MBTL1DAORAB9ATSHRLMNA
SCHEMBL7116372 0.74 L3MBTL1 (0.59) FFAR4L3MBTL1DAOMETRAB9A
SCHEMBL7097252 0.72 MAPT (0.45) FFAR4L3MBTL1RAB9ANPC1MAPK1
SCHEMBL7084333 0.72 L3MBTL1 (0.42) FFAR4L3MBTL1DAORAB9ATSHR
SCHEMBL12747582 0.72 L3MBTL1 (0.62) FFAR4L3MBTL1DAOMETRAB9A
SCHEMBL7087242 0.72 L3MBTL1 (0.40) FFAR4L3MBTL1DAOMETRAB9A
SCHEMBL27536208 0.71 L3MBTL1 (0.66) FFAR4L3MBTL1DAOSPHK2SPHK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa MERCK PATENT GMBH (DE) 2003-10-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030199698-A1 Carbamic acid esters as inhibitors of factor xa F11, F12, F13A1 FFAR4 1040/4885L3MBTL1 1569/4885DAO 1162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.