Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12747582 | 0.86 | L3MBTL1 (0.62) | L3MBTL1FFAR4FFAR1DAOTSHR | |
| SCHEMBL6565112 | 0.82 | L3MBTL1 (0.59) | L3MBTL1FFAR4DAOTSHRKMT2A | |
| SCHEMBL27536208 | 0.81 | L3MBTL1 (0.66) | L3MBTL1FFAR4DAOTSHRKMT2A | |
| SCHEMBL1300632 | 0.80 | L3MBTL1 (0.70) | L3MBTL1FFAR4S1PR1DAOTSHR | |
| SCHEMBL6326326 | 0.80 | ALDH1A1 (0.59) | L3MBTL1FFAR1TSHRKMT2ARAB9A | |
| SCHEMBL13678306 | 0.79 | S1PR1 (0.62) | S1PR1 | |
| SCHEMBL10066488 | 0.79 | L3MBTL1 (0.72) | L3MBTL1FFAR4S1PR1DAOTSHR | |
| SCHEMBL12747584 | 0.78 | L3MBTL1 (0.57) | L3MBTL1FFAR4DAORAB9ALMNA | |
| SCHEMBL25254573 | 0.78 | KIFC1 (0.60) | L3MBTL1FFAR4S1PR1 | |
| SCHEMBL30497131 | 0.78 | KIFC1 (0.60) | L3MBTL1FFAR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
| EP-1257530-A1 | AMINOSULFONYLBIPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2002-11-20 | — | — | EP | disclosed |
| WO-2001062717-A1 | AMINOSULFONYLBIPHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | L3MBTL1 2669/4885FFAR4 2486/4885FFAR1 2330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.