Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28627118 | 0.76 | MAOA (0.45) | HTR2AMAOAMAOBATMGPR3 | |
| SCHEMBL8516774 | 0.70 | MAOA (0.54) | HTR2AMAOAMAOBATMGPR3 | |
| SCHEMBL27885617 | 0.69 | HTR2A (0.52) | HTR2AATMGPR3CYP1A2CYP2D6 | |
| SCHEMBL29116619 | 0.67 | HTR2A (0.50) | HTR2AMAOAGPR3CYP1A2KDM4E | |
| SCHEMBL8516771 | 0.67 | MAOA (0.50) | HTR2AMAOAMAOBATMCYP2C9 | |
| SCHEMBL25171318 | 0.65 | LMNA (0.54) | HTR2AMAOAMAOBGPR3CYP1A2 | |
| SCHEMBL1304934 | 0.65 | HTR2A (0.48) | HTR2AGPR3CYP1A2CYP2D6HDAC3 | |
| SCHEMBL29490167 | 0.65 | HTR2A (0.48) | HTR2AGPR3CYP1A2CYP2D6HDAC3 | |
| SCHEMBL70993 | 0.65 | LMNA (0.54) | HTR2AMAOAMAOBGPR3CYP1A2 | |
| SCHEMBL9297178 | 0.65 | HTR2A (0.48) | HTR2AMAOAGPR3CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199542-A1 | Farnesyltransferase inhibitors | WEINSTOCK, STEVEN F. | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199542-A1 | Farnesyltransferase inhibitors | FNTA, FNTB, LCAT | HTR2A 4721/4885MAOA 2168/4885MAOB 1531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.