Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 10/20 | 0.42 |
| ▸ | APOB | P04114 | 7/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793408 | 0.91 | TP53 (0.43) | MTTPAPOBSMOTP53MAPT | |
| SCHEMBL6788870 | 0.88 | LMNA (0.51) | MTTPAPOBSMOMAPTUGCG | |
| SCHEMBL6794352 | 0.86 | MTTP (0.41) | MTTPAPOBSMOTP53MAPT | |
| SCHEMBL7084370 | 0.83 | MTTP (0.43) | MTTPAPOBSMOTP53MAPT | |
| SCHEMBL7085681 | 0.80 | MTTP (0.47) | MTTPAPOBSMOUGCGGAA | |
| SCHEMBL6789164 | 0.78 | TP53 (0.45) | MTTPAPOBSMOTP53MAPT | |
| SCHEMBL6798629 | 0.78 | KMT2A (0.37) | MTTPMAPTGAASMN1; SMN2KDM4E | |
| SCHEMBL6795504 | 0.77 | MTTP (0.42) | MTTPAPOBSMOTP53MAPT | |
| SCHEMBL6795017 | 0.75 | TP53 (0.50) | MTTPAPOBTP53MAPTSMN1; SMN2 | |
| SCHEMBL6799168 | 0.75 | TP53 (0.49) | MTTPAPOBSMOTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |