SCHEMBL6794352

SCHEMBL6794352

CN(C(=O)OC(C)(C)C)c1nc(CCN(C(=O)O)c2ccc(NC(=O)c3ccccc3-c3ccc(C(F)(F)F)cc3)cc2)cs1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MTTP P55157 14/20 0.41
APOB P04114 7/20 0.40
SMO Q99835 1/20 0.40
TP53 P04637 2/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6798629 0.92 KMT2A (0.37) MTTPMAPT
SCHEMBL6793408 0.86 TP53 (0.43) MTTPAPOBSMOTP53MAPT
SCHEMBL7084367 0.86 MTTP (0.42) MTTPAPOBSMOTP53MAPT
SCHEMBL6788870 0.86 LMNA (0.51) MTTPAPOBSMOMAPTLMNA
SCHEMBL6795504 0.86 MTTP (0.42) MTTPAPOBSMOTP53MAPT
SCHEMBL6793746 0.81 SMO (0.53) MTTPAPOBSMO
SCHEMBL6788065 0.81 SMO (0.42) MTTPAPOBSMO
SCHEMBL7084370 0.81 MTTP (0.43) MTTPAPOBSMOTP53MAPT
SCHEMBL6794499 0.80 CYP3A4 (0.40) MTTPTP53MAPTLMNA
SCHEMBL6500248 0.79 APOB (0.45) MTTPAPOBTP53MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 MTTP 363/4885APOB 1/4885SMO 2094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.