Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 7/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089476 | 0.94 | OPRM1 (0.56) | OPRM1TMEM97HTR2ATP53CCR5 | |
| SCHEMBL340673 | 0.87 | HTR2A (0.63) | OPRM1TMEM97HTR2A | |
| SCHEMBL7084339 | 0.87 | HTR2A (0.63) | OPRM1TMEM97HTR2A | |
| SCHEMBL340916 | 0.82 | HTR2A (0.67) | OPRM1TMEM97HTR2A | |
| SCHEMBL342207 | 0.82 | OPRM1 (0.52) | OPRM1TMEM97HTR2ATP53CCR5 | |
| SCHEMBL9994976 | 0.82 | OPRM1 (0.71) | OPRM1TMEM97TP53CCR5 | |
| SCHEMBL341156 | 0.81 | TACR1 (0.58) | OPRM1TMEM97HTR2A | |
| SCHEMBL4911920 | 0.81 | HTR2A (0.62) | HTR2A | |
| Hydrochloric Acid SCHEMBL4212243 | 0.80 | HTR2A (0.61) | HTR2A | |
| SCHEMBL341792 | 0.80 | OPRM1 (0.53) | OPRM1TMEM97HTR2ACCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220316-A1 | Azacyclic compounds | ACADIA PHARMACEUTICALS INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220316-A1 | Azacyclic compounds | HTR6, TPMT, HNMT | OPRM1 210/4885TMEM97 325/4885HTR2A 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.