Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6951927 | 0.91 | TACR1 (0.36) | SLC6A1SLC6A11TACR1HTTRORC | |
| SCHEMBL7077994 | 0.89 | SLC6A1 (0.41) | SLC6A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7079956 | 0.87 | SLC6A1 (0.35) | SLC6A1SLC6A11TACR1HTTRORC | |
| SCHEMBL7081088 | 0.84 | REN (0.43) | CHRM3 | |
| SCHEMBL7080691 | 0.83 | MEN1 (0.38) | TACR1HTTMEN1KMT2A | |
| SCHEMBL6950872 | 0.83 | HTT (0.45) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6959991 | 0.83 | S1PR1 (0.46) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL7076319 | 0.82 | KDM1A (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6957302 | 0.82 | S1PR1 (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6951206 | 0.81 | MEN1 (0.39) | TACR1HTTRORCMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |