Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CCKBR | P32239 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982745 | 0.74 | NPC1L1 (0.39) | GFERCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6984266 | 0.73 | NPC1L1 (0.41) | GFERCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6987412 | 0.69 | CHRM2 (0.48) | GFERCHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL7084907 | 0.68 | CCKBR (0.63) | CCKBR | |
| SCHEMBL7088452 | 0.68 | CHRM2 (0.58) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4075040 | 0.66 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL10688723 | 0.65 | CCKBR (0.49) | CCKBRMAPT | |
| SCHEMBL7246586 | 0.65 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL4075043 | 0.65 | CHRM2 (0.56) | CHRM2CHRM4CHRM1CHRM3MEN1 | |
| SCHEMBL29048162 | 0.63 | PTGDR2 (0.43) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294716-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | Bristol-Myers Squibb Company (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096331-A1 | LACTAM INHIBITORS OF FACTOR XA AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |