SCHEMBL7085384

SCHEMBL7085384

CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(C)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRA P10827 16/20 1.00
THRB P10828 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7088673 0.89 THRA (1.00) THRATHRB
SCHEMBL7085090 0.88 THRA (1.00) THRATHRB
SCHEMBL7088287 0.88 THRA (0.78) THRATHRB
SCHEMBL13932932 0.87 THRA (0.78) THRATHRB
SCHEMBL7089419 0.87 THRA (0.77) THRATHRB
SCHEMBL7089550 0.87 THRA (0.77) THRATHRB
SCHEMBL7089354 0.87 THRA (0.77) THRATHRB
SCHEMBL6515949 0.84 THRA (0.73) THRATHRB
SCHEMBL6511153 0.84 THRA (0.72) THRATHRB
SCHEMBL6513266 0.83 THRA (0.75) THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1268422-A1 INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES Bayer Aktiengesellschaft (DE) 2003-01-02 EP disclosed
WO-2001070687-A1 INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES BAYER AKTIENGESELLSCHAFT (DE) 2001-09-27 WO disclosed