Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085384 | 0.89 | THRA (1.00) | THRATHRB | |
| SCHEMBL7089354 | 0.87 | THRA (0.77) | THRATHRB | |
| SCHEMBL7130895 | 0.80 | THRA (0.66) | THRATHRB | |
| SCHEMBL6663299 | 0.78 | THRA (0.70) | THRATHRB | |
| SCHEMBL7135874 | 0.78 | THRA (0.73) | THRATHRB | |
| SCHEMBL7085090 | 0.77 | THRA (1.00) | THRATHRB | |
| SCHEMBL7082734 | 0.76 | THRA (0.70) | THRATHRB | |
| SCHEMBL13932932 | 0.76 | THRA (0.78) | THRATHRB | |
| SCHEMBL6739756 | 0.76 | THRA (0.62) | THRATHRB | |
| SCHEMBL7088509 | 0.76 | THRA (0.78) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268422-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | Bayer Aktiengesellschaft (DE) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070687-A1 | INDOLES FOR TREATING DISEASES THAT CAN BE TREATED USING THYROID HORMONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-27 | — | — | WO | disclosed |