Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085445 | 1.00 | NPC1 (0.32) | NPC1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28548694 | 0.70 | HDAC4 (0.30) | — | |
| SCHEMBL27970251 | 0.70 | — | — | |
| SCHEMBL7086931 | 0.69 | ALDH1A1 (0.33) | NPC1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7086930 | 0.69 | ALDH1A1 (0.33) | NPC1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL28410189 | 0.68 | NPC1 (0.33) | NPC1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL28725270 | 0.64 | MEN1 (0.32) | NPC1MEN1KMT2ARAB9A | |
| SCHEMBL28800061 | 0.64 | FTO (0.31) | NPC1ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7085065 | 0.63 | — | — | |
| SCHEMBL7085063 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112538055-A | Preparation method of benzotriazole ultraviolet absorbent | 西安凯立新材料股份有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-108148009-B | Method for preparing benzotriazole ultraviolet absorbent by adopting catalytic hydrogen transfer method | 天津利安隆新材料股份有限公司 | 2020-05-12 | — | — | CN | disclosed |
| EP-1351944-A1 | METHOD FOR PREPARING 2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE | LG Chem Ltd. (KR) | 2003-10-15 | — | — | EP | disclosed |
| US-6559316-B2 | Reacting o-nitrophenylazohydroxyphenyl compound with hydrazine hydrate; reduction in presence of water, zinc powder, and sulfuric acid with/without phase transfer catalyst | LG CHEM, LTD. (KR) | 2003-05-06 | — | — | US | disclosed |
| US-20030050480-A1 | METHOD FOR PREPARING 2-(2-HYRDROXYPHENYL)-2H-BENZOTRIAZOLE | LG CHEM, LTD. (KR) | 2003-03-13 | — | — | US | disclosed |
| WO-2002055508-A1 | METHOD FOR PREPARING 2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE | LG CHEM, LTD. (KR) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030050480-A1 | METHOD FOR PREPARING 2-(2-HYRDROXYPHENYL)-2H-BENZOTRIAZOLE | CYP8B1, CYP4Z1, CBR1 | NPC1 1433/4885ALDH1A1 376/4885LMNA 1212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.