Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086451 | 0.89 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNATP53TSHR | |
| SCHEMBL9423197 | 0.80 | ESR1 (0.44) | ALDH1A1SMN1; SMN2LMNATP53TSHR | |
| SCHEMBL9452030 | 0.79 | ATM (0.39) | ALDH1A1SMN1; SMN2LMNATP53TSHR | |
| SCHEMBL7085729 | 0.78 | POLB (0.41) | ALDH1A1SMN1; SMN2LMNAKMT2ANPC1 | |
| SCHEMBL7080931 | 0.78 | NPC1 (0.44) | ALDH1A1NPC1CHRM2CHRM1CHRM3 | |
| SCHEMBL7088355 | 0.76 | NPC1 (0.42) | ALDH1A1NPC1CHRM2CHRM1CHRM3 | |
| SCHEMBL29025475 | 0.75 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2LMNATP53TSHR | |
| SCHEMBL9452039 | 0.74 | — | — | |
| SCHEMBL7081222 | 0.74 | LMNA (0.43) | LMNAKMT2A | |
| SCHEMBL3507290 | 0.73 | LMNA (0.58) | ALDH1A1SMN1; SMN2LMNATSHRPDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |