Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.67 |
| ▸ | PAM | P19021 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 3/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27527310 | 0.85 | MAOB (0.71) | MAOBPAMMAOAHDAC1ADORA1 | |
| SCHEMBL29236549 | 0.81 | MAOB (0.67) | MAOBPAMMAOAHDAC1ADORA1 | |
| SCHEMBL14276954 | 0.81 | MAOB (0.67) | MAOBPAMMAOAHDAC1ADORA1 | |
| SCHEMBL11974575 | 0.79 | PAM (0.70) | MAOBPAMMAOAHDAC1ADORA1 | |
| SCHEMBL9113145 | 0.79 | PAM (0.70) | MAOBPAMMAOAHDAC1PTGER4 | |
| SCHEMBL9113139 | 0.79 | PAM (0.70) | MAOBPAMMAOAHDAC1PTGER4 | |
| SCHEMBL582727 | 0.78 | PAM (1.00) | MAOBPAMMAOAHDAC1PTGER4 | |
| SCHEMBL4296099 | 0.78 | PAM (0.76) | MAOBPAMMAOAHDAC1PTGER4 | |
| SCHEMBL2148302 | 0.78 | PAM (1.00) | MAOBPAMMAOAHDAC1PTGER4 | |
| SCHEMBL4296095 | 0.78 | PAM (0.76) | MAOBPAMMAOAHDAC1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003074534-A9 | REAGENTS FOR ASYMMETRIC ALLYLATION, ALDOL, AND TANDEM ALDOL AND ALLYLATION REACTIONS | UNIV COLUMBIA (US) | 2003-11-20 | — | — | WO | disclosed |