Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MTTP | P55157 | 9/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793515 | 0.89 | MTTP (0.63) | SORT1LMNANPC1RAB9APOLB | |
| SCHEMBL6795684 | 0.78 | SMO (0.65) | SORT1LMNANPC1RAB9APOLB | |
| SCHEMBL4181950 | 0.77 | LMNA (0.70) | SORT1LMNANPC1RAB9APOLB | |
| SCHEMBL14082655 | 0.76 | LMNA (0.62) | SORT1LMNANPC1RAB9APOLB | |
| SCHEMBL6800075 | 0.75 | SMO (0.64) | SORT1LMNANPC1RAB9APOLB | |
| SCHEMBL6638865 | 0.74 | SMO (0.53) | SORT1LMNAMTTPHTTSMO | |
| SCHEMBL15903134 | 0.74 | SORT1 (0.91) | SORT1LMNANPC1RAB9APOLB | |
| SCHEMBL15903132 | 0.74 | SORT1 (1.00) | SORT1LMNANPC1RAB9APOLB | |
| SCHEMBL7087226 | 0.73 | SMO (0.49) | SORT1LMNAHTTKMT2ASMO | |
| SCHEMBL11626193 | 0.73 | SORT1 (0.65) | SORT1LMNANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1478077-A | Benzamide compounds as APO B secretion inhibitors | ����ҩƷ��ҵ��ʽ���� | 2004-02-25 | — | — | CN | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |