Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788349 | 0.86 | SMO (0.59) | LMNATRPV1SMO | |
| SCHEMBL6489790 | 0.78 | TRPV1 (0.50) | TRPV1SMO | |
| SCHEMBL6793985 | 0.76 | SMO (0.60) | LMNATRPV1SMOSMN1; SMN2 | |
| SCHEMBL7083798 | 0.76 | GRM4 (0.44) | LMNASMOCYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL6490419 | 0.75 | L3MBTL1 (0.46) | TRPV1CYP1A2CYP2C19SMN1; SMN2CTNNB1 | |
| SCHEMBL6788522 | 0.74 | SMO (0.59) | LMNATRPV1SMOSMN1; SMN2RAB9A | |
| SCHEMBL7086840 | 0.73 | ALDH1A1 (0.44) | LMNATRPV1PTPRC | |
| SCHEMBL6801341 | 0.73 | SMO (0.61) | LMNATRPV1SMOSMN1; SMN2 | |
| SCHEMBL6644225 | 0.73 | KDM4E (0.44) | LMNACYP1A2CYP2C19SMN1; SMN2CTNNB1 | |
| SCHEMBL6788368 | 0.73 | SMO (0.61) | LMNATRPV1SMOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |